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GLP 1 based therapies for diabetes, obesity and beyond Nature Reviews Drug Discovery Tirzepatide (TZP) differentially induces internalization of the GIP and Download Scientific Diagram Artificial Intelligence Driven Prediction of Glucagon Like Peptide 1 Receptor Agonist Eligibility in Obesity Gitanjali Srivastava, Ayush V. Madhar, You Chen, 2025 Exploring glucagon like peptide 1 receptor agonists as potential disease modifying agent in psychiatric and neurodevelopmental conditions: evidence from a drug target Mendelian randomization BMC Psychiatry Springer Nature Link Sometimes patients ask in a hushed voice Do you prescribe microdoses of GLP 1s? like it's some form of underground drug dealing. Whilst I definitely do not prescribe compounded GLP 1 medications (we have GLP 1 Drug Can Cause Rare, Potentially Blinding Side Effect, EMA Warns MedPage Today
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Best in 7 days
Best in 7 days
Best in 7 days
Best in 7 days
4.4 ★★★★★
Based on 2269 reviews
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Product Reviews
★★★★★ 3
Samples great, purchased product not
Style: Restorative Protective Cream-1.3 Fl Oz
My dermatologist recommended this cream after a laser procedure, and gave me some samples to take home. I found the thick, smooth cream calming and protective for my irritated skin. The zinc oxide leaves a whitish cast at first, which does tend to fade after it sinks in, but it could be problem if you have darker skin. Not an issue for me since I’m pale.
Because I liked the samples, I ordered two full-size tubes. Both arrived with the product inside completely separated. The texture was nothing like the samples. I opened the first tube and clear, watery liquid spilled everywhere. I quickly recapped it, shook and squeezed the tube as much as possible to try to re-emulsify the product, and it remained stubbornly separated, with chunky white paste suspended in thin liquid. I’ve thoroughly shaken the second tube and continue to hear the sloshing of thin liquid. So apparently once the cream has separated, it will not re-mix.
I don’t know what caused the unacceptable condition of the product—manufacturing variation, storage conditions prior to shipping, or conditions during shipment. Whatever it was, I would not buy this product in this way again. The samples were a five star product. The full size product I received was zero stars.
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Reviewed in the United States on February 15, 2026
★★★★★ 4
Helped calm my damaged skin barrier, but expect stinging on very raw skin
Style: Restorative Protective Cream-1.3 Fl Oz
I bought this because I severely damaged my skin barrier and needed something gentle that would help my skin calm down and heal. My skin was extremely sensitive, raw, irritated, tight, and honestly uncomfortable even with water touching it.
This did help, but I do want to mention that if your skin is VERY damaged or raw, there can be some stinging at first. I experienced that myself during the first few applications. The stinging didn’t last long for me, but I think it’s important to mention because people with damaged barriers are usually desperate for relief and can panic when products sting.
What ended up helping me most was using this as part of a simple barrier repair routine instead of using it alone.
What I personally did:
* Wet my face first with either water or Avène Thermal Spring Water so my skin was damp but not soaking wet
* Applied the Avène Cicalfate onto the damp skin
* At night, I sealed everything in with CeraVe Healing Ointment (Aquaphor would probably work too)
I repeated this every night before bed and sometimes during the day if I was staying home.
If I was leaving the house during the day, I would do the same steps but use sunscreen instead of sealing with ointment. I honestly think sunscreen is extremely important when your skin barrier is damaged and trying to heal because irritated skin feels even more sensitive when exposed to sunlight.
I used this day and night, very easy to use, and didn’t experience breakouts from it. The texture is thick but comforting once applied, especially when your skin feels dry and stripped.
Overall, I would buy this again. I don’t think it’s some overnight miracle product, but it genuinely helped my skin calm down and recover when my barrier was damaged. I personally didn’t notice any strong fragrance, which I appreciated since my skin was already extremely irritated. I also like how versatile this product is. Even though I originally bought it for barrier damage, I can see why people use it for irritation from retinol, over-exfoliating, dry patches, or skin that just feels compromised in general.
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Reviewed in the United States on May 14, 2026
★★★★★ 5
Holy Grail of Moisturizers
Style: Restorative Protective Cream-3.3 Fl Oz
I bought this after hearing a dermatologist on Instagram rave about this cream and now I see why. As someone who suffers from pretty severe eczema this is my go to holy grail for flair ups. Perfect for sensitive skin and can be used daily. It is very thick so provides a thick layer of moisture on your skin. I will say I have bought 2 sizes in this and the smaller size (1.3fl oz) did separate and had a liquid part that would come out. I have bought numerous tubes of the larger size (3.3fl oz) and never had an issue with separation with the larger size. I’m learning as I get older that more expensive does not mean better quality skincare. This is one that is not only affordable, but will also give you noticeable results. I have everyone in my whole family using this product!
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Reviewed in the United States on May 17, 2026
★★★★★ 5
GREAT STUFF!!!
THIS STUFF IS AMAZING!!! It really does have the consistency of a light mousse, and it goes on so evenly! I have combination skin that changes in dryness and oiliness through the month and by season, but this gives very consistent coverage that doesn't make me break out! It gives my face a matte appearance (but not flat in color) and blends well with my other make up (blush, bronzer, etc.). Great for hiding bumps, acne, and redness too! It also doesn't crease up under my eyes. I am usually the lightest or next to lightest shade in foundations (neutral undertones), and when I first squeezed some out of the tube I thought it would be way too dark/tan for me, but it matches my skin perfectly! The coverage lasts all day for me without reapplication.
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Reviewed in the United States on May 29, 2015
★★★★★ 5
"Blur" is A Good Word For This great Product
This is one of the best BB's I have ever used. I have a strange combination of oily skin that is dry in other areas and also very sensitive. I need something that moisturizes but keeps oil at bay at the same time. SPF is essential and non irritating to my skin and especially my eyes. Kind of hard to find.
PROS:
All of the above was met and it creates a flawless finish. The word "blur" aptly describes the look. I took a picture so you can see the color and how it looks when applied to my hand. Just flawless!
Controls oil
Does not settle into the fine lines around the mouth and eyes.
CONS:
Has a yellow undertone. I have fair skin with a warm undertone so I can wear this, but others may not be able to.
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Reviewed in the United States on February 8, 2016
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